Reservoir is building a new class of therapy that targets the blood-brain barrier itself — its structure, its integrity, its function — rather than treating around it.
The blood-brain barrier is the most selective membrane in the body. It decides what enters the brain and what stays out. When its integrity breaks down, the consequences reach across a wide range of neurological disease — yet no approved therapy directly targets it.
Barrier dysfunction is a feature of many CNS conditions — a common thread that a healing approach could address at its source.
Decades of drug development have focused on getting molecules across the barrier. Far less has asked a more fundamental question: how do we keep the barrier healthy in the first place?
Developing therapeutics aimed at repairing barrier function at the cellular level.
A mechanism with the potential to extend across conditions where barrier health matters.
An early-stage platform with a defined path from discovery toward the clinic.
Neuroscience is finally asking structural questions about the brain, not just chemical ones. The tools to study the blood-brain barrier in detail are better than ever — and the thesis that healing it could change the course of neurological disease is newly testable.
Reach out — we're glad to talk through the platform with serious scientists and investors.